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Ceramide Glycanase Kit


  • Product Code: LZ-CER-HM-KIT

  • Size 55 µL

https://www.ludger.com/product-catalogue/ceramide-glycanase-kit/

Ceramide glycanase can be used to deglycosylate a variety of glycosphingolipids by cleaving the β-glycosyl linkage. Ceramide glycanase allows the identification of glycosylation patterns of glycosphingolipids through cleaving the glycan moiety and making it accessible to LudgerTag labelling technology.


Glycosphingolipids (GSLs) are the most abundant and diverse class of glycolipids in animals (and are also present in fungi, plants, and invertebrates). Glycans present on GSLs have important roles in physiology and pathology. The ability to identify and measure GSLs is important for research in developmental neurobiology as well as lysosomal storage diseases such as Tay-Sachs and Gaucher’s disease. There is also growing interest in GSLs as possible targets for immunotherapy.


Ceramide glycanase is an enzyme used to release glycans from GSLs to enable their characterisation. It cleaves glycans including GM1, GM2 and GM3 by cleaving the β-glycosyl linkage. Glycans can then be labelled using LudgerTag labelling technology. We have purified ceramide glycanase from Hirudo medicinalis and offer this in a kit along with buffer and GM1 glycolipid substrate.


Kit includes enzyme, reaction buffer and GM1 standard. Sufficient for up to 150 reactions.


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关于定制的糖基化分析服务和糖基化分析方法的开发;药物糖基化分析的培训;提供糖基化分析试剂盒和试剂等。

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